Research Summary: Bioprospection, Metabolomics, Pharmacology, and Nanobiotechnology, as well as Herbal Product Development are the major research areas. We elucidate molecular mechanisms of actions of therapeutic phytochemicals for their anti-inflammatory, anti-diabetic, anti-obesity, anti-oxidant and anti-quorum sensing activities. We also develop smart drug delivery systems using organic nanoparticles to enhance their bio-availability and therapeutic potentials.

Published over 69 SCI journal articles (Hi 35, citations >8200 as per Google Scholar), 2 patents awarded, 5 patents filed, 12 technologies/herbal products developed, 8 technologies/products licensed, 10 book chapters in his research areas and edited 1 book.

Young Scientist Award form Biotech Research Society, India (BRSI), Industrial Medal Award from BRSI, Young Scientist Fellowship Award from Department of Science and Technology are received.

• Sharma V.K., Prateeksha P, Singh, S.P., Rao Ch.V., Singh B. N. (2024). Nyctanthes arbor-tristis bioactive extract ameliorates LPS-induced inflammation through the inhibition of NF-κB signalling pathway. Journal of Ethnopharmacology 320, 117382.


• Paliya, B.S., Sharma, V.K., Sharma, M., Diwan, D., Aminabhavi, T.M., Rajauria, G., Gupta, V.K., Singh, B.N. (2023). Protein-polysaccharide nanoconjugates for the delivery of plant-derived nutraceuticals. Food Chemistry 428, 136709.


• Prateeksha P, Sharma V.K., Nagpoore N., Jadoun V., Rao Ch.V., Singh B. N. (2023). Bacteria-responsive multidrug delivery nanosystem for combating long-term biofilm-associated infections. Advanced Functional Materials 2214852.


• Paliya, B.S., Sharma, V.K., Tuohy, M.G., Singh, H.B., Koffas, M., Benhida, R., Tiwari, B.K., Kalaskar, D.M., Singh, B.N., Gupta, V.K. (2023). Bacterial glycobiotechnology: A biosynthetic route for the production of biopharmaceutical glycans. Biotechnology Advances 67, 108180.


• Kumar, S., Paliya, B.S. and Singh B.N. (2022). Superior inhibition of virulence and biofilm formation of Pseudomonas aeruginosa PAO1 by phyto-synthesized silver nanoparticles through anti-quorum sensing activity. Microbial Pathogenesis 170, 105678.


• Sharma, V.K., Prateeksha, Singh, S.P., Singh, B.N.†, Rao, Ch.V. and Barik, S.K. (2022). Nanocurcumin potently inhibits SARS-CoV-2 spike protein-induced cytokine storm by deactivation of MAPK/NF-κB signalling in epithelial cells. ACS Applied Bio Materials 5, 2, 483–491.


• Sharma, V.K., Usmani, Z., Sharma, M., Pandey, A., Singh, B.N.†, Tabatabaei, M. and V.K. Gupta (2022). Tailored enzymes as next-generation food-packaging tools. Trends in Biotechnology 40, 1004-1017.


• Sharma, V.K., Prateeksha, Gupta, S.C., Singh, B.N.†, Rao, Ch.V. and Barik, S.K. (2022). Cinnamomum verum-derived bioactives-functionalized gold nanoparticles for prevention of obesity through gut microbiota reshaping. Materials Today Bio 13, 100204. 2022


• Singha, K.M., Singh, B.N. and Pandey, P. (2021). Host-specific endophytic microbiome diversity and associated functions in three varieties of scented black rice are dependent on growth stage. Scientific Reports 11, e12259.


• Prateeksha, V.K. Sharma, X. Liu, D.A. Oyarzún, A.M. Abdel-Azeem, A.G. Atanasov, A.E.L. Hesham, S.K. Barik, V.K. Gupta, and Singh, B.N. (2021). Microbial polysaccharides: an emerging family of natural biomaterials for cancer therapy and diagnostics. Seminars in Cancer Biology doi.org/10.1016/j.semcancer.2021.05.021.


• Prateeksha, Bajpai R, Rao Ch V, Upreti DK, Barik SK, Singh, B.N. (2021). Chrysophanol-functionalized silver nanoparticles for anti-adhesive and antibiofouling coating to prevent urinary catheter associated infections. ACS Applied Nano Materials 4(2), 1512–1528.


• Singh, B.N., Prateeksha, Jadoun, V., Ch.V. Rao and Barik, S.K. Anti-fungal formulation for controlling vulvovaginal candidiasis. Indian Patent 0104NF2018.


• Barik, S.K., Singh, B.N., Hiland, K., Gagurel, P., Prateeksha. A herbal emulsion based anti-acne formulation and a process for the preparation thereof. Indian Patent 0027NF2019.


• Barik, S.K., Singh, B.N., Ch.V. Rao, Prateeksha. Herbal emulsion based formulation of an essential oil for dental treatment and a process for preparation thereof. Indian Patent 0096NF2019.


• Singh, B.N., Barik, S.K., Prateeksha and Ch.V. Rao. Synergistic herbal formulation useful for the protection of cavity formation and toothache Indian Patent 0221NF2019.


• Singh, B.N., Barik, S.K., Ch.V. Rao and Prateeksha. Synergistic herbal gel useful for controlling inflammation and pain of teeth and gums. Indian Patent 0222NF2019.


• Singh, B.N., Barik, S.K., Prateeksha, Gupta, S.C., Sharma, V.K., and Rao Ch.V. A novel formulation of highly bioavailable curcumin and method of preparation thereof. Indian Patent 0025NF2021.


• Singh, B.N., Barik, S.K., Prateeksha, Gupta, S.C., Sharma, V.K. and Rao Ch.V. A Novel Nanocomposition of bioavailable flavonoids and method of preparation thereof. Indian Patent 0053NF2021.

• Research Scholar: 5


• Post-Doctoral Fellows: 0


• Project Staff: 2

• Pharmacology Division


• CSIR-National Botanical Research Institute, Lucknow-226001


• E-mail: bn.singh@nbri.res.in


• Phone: 0522-2297900 (Office)